Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-st

chapter 1|4 pages

■ Introduction

chapter 2|22 pages

■ Transcription Networks: Basic Concepts

chapter 3|14 pages

■ Autoregulation: A Network Motif

chapter 4|34 pages

■ The Feed-Forward Loop Network Motif

chapter 8|16 pages

■ Robust Patterning in Development

chapter 9|18 pages

■ Kinetic Proofreading

chapter 10|22 pages

■ Optimal Gene Circuit Design

chapter 11|18 pages

■ Demand Rules for Gene Regulation

chapter 12|8 pages

■ Epilogue: Simplicity in Biology