Since the publication of the first edition, the field has changed dramatically. Scientists can now explicitly consider 3D features in quantitative structure-activity relationship (QSAR) studies and often have the 3D structure of the macromolecular target to guide the 3D QSAR. Improvements in computer hardware and software have also made the methods

chapter 1|14 pages

Overview of Quantitative Drug Design

chapter 5|16 pages

Biological Data

chapter 10|54 pages

Case Studies