ABSTRACT

Acute toxicology testing constitutes the first line of defense against potentially dangerous chemicals. This book provides a detailed presentation of protocols for each of the common designs, reviews their development and objectives, discusses the types of data they generate, and examines the current status of alternative test designs and models. F

chapter 4|30 pages

—OCULAR IRRITATION TESTING

chapter 5|36 pages

—DERMAL SENSITIZATION

chapter 6|24 pages

—PHOTOSENSITIZATION/PHOTOTOXICITY

chapter 7|42 pages

—LETHALITY TESTING

chapter 9|38 pages

—ACUTE SYSTEMIC TOXICITY TESTS

chapter 10|48 pages

—ROUTES, FORMULATIONS AND VEHICLES

chapter 12|42 pages

—STATISTICAL ANALYSIS FOR ACUTE TOXICOLOGY

chapter 13|64 pages

—ACUTE INHALATION

chapter 14|26 pages

—PROBLEMS AND ISSUES

chapter |1 pages

A. Regulatory Acronyms

chapter |27 pages

B. Moving Average Tables

chapter C|8 pages

Vehicles