ABSTRACT
This work offers succinct, medically-oriented coverage of biochemistry, examining biologically important materials and presenting the properties of nucleic acids as well as nucleic acid metabolism. Each metabolic process is integrated in a review of overall energy metabolism, diabetes and starvation. A solutions manual is available to instructors o
TABLE OF CONTENTS
chapter 4|6 pages
Amino Acids and Proteins
After readin g this chapter, the student shoul d 1. Kno w th e names , structures , an d classificatio n o f al l amin o acids and their side chains present i n proteins, and be familiar with thei r physica l an d chemica l properties , suc h a s con - formation, absorptio n o f ultraviole t light , an d reaction s wit h
chapter 5|6 pages
Proteins with Biological Activity: Enzyme s
After completin g this chapter, the student shoul d the type of reactio n catalyzed b y each class . 3. Understan
chapter 6|28 pages
Vitamins and Mineral s
After completing this chapter, the student shoul d 1. Recogniz e th e structur e o f eac h vitami n an d it s coenzyme . 2. Kno w th e type o f reactio n catalyze d b y each coenzym e an d be able to identif y the active site of the coenzyme . 3. Kno w the etiology o f various vitamin deficiency diseases .
chapter 7|4 pages
Proteins with Biological Activity: Blood Proteins
After completin g this chapter, the student shoul d 1. Kno w th e genera l propertie s o f blood : th e function s o f it s cellular element s an d th e meanin g o f the term s plasma, se- rum, hematocrit, plasma proteins, hemoglobin, coagulation. 2. Kno w the general properties of hemoglobin and myoglobin —
chapter 9|1 pages
Carbohydrates, Lipids, and Related Structures
After completin g this chapter, the student shoul d bohydrates: mono-, di-, oligo-, and polysaccharides. B e famil- iar wit h thei r stereochemica l properties , reducin g properties , terminology use d t o designat e simila r sugar s (e.g. , anomer s
chapter 10|2 pages
Nucleic Acid Chemistry and Nucleotid e Metabolism
After completin g this chapter, the student shoul d 1. Understan d th e propertie s o f purin e an d pyrimidin e base s and nucleosides , an d nucleotide s wit h varyin g amount s o f phosphate. Recogniz e th e structure s o f th e variou s xan -
chapter 11|19 pages
DNA and RNA Information Flow
After completing this chapter, the student shoul d . Understan d th e Messelson-Stah l experimen t an d it s interpre - tation to verify semiconservative DN A replication . 2. Kno w th e role s o f DN A polymeras e I , II , III , an d eukaryoti c DNA polymerases , th e role s o f primers , helicases , single -
chapter 13|16 pages
Regulation of Gene Expressio n
After completin g this chapter, the student shoul d zyme repression , coordinat e repression , 2. Understan d th e functio n o f th e opero n an d it s components . 3. Kno w th e role s o f a regulato r gene , represso r an d com -
chapter 16|20 pages
Action of Hormones and Prostaglandins
After completin g the chapter, the student shoul d 1. Explai n th e arrangemen t o f th e hypothalamus-pituitar y hor - mone system , includin g th e functio n o f hypothalami c releas e and releas e inhibitor y factors ; tropic an d nontropi c hormone s elaborated b y th e anterior , intermediary , an d posterio r pitu -
chapter 17|20 pages
Overview of Metabolism an d Oxidative Phosphorylation
After completing this chapter, th e student should : gluconeogenesis, th e Kreb s cycle , ure a cycle , lipogenesis , lipolysis, an d oxidatio n an d describ e ho w thes e pathway s
chapter 18|2 pages
Digestion and Metabolism o f Carbohydrates
After completin g this chapter, the student shoul d 1. Kno w th e name s an d mode s o f action o f carbohydrat e diges - tive enzymes found in the saliva and the small intestine, includ- ing th e amylase s an d disaccharidases ; revie w ho w glucos e and other hexose s ar e absorbed .
chapter 20|1 pages
Protein and Amino Acid Metabolis m
After completin g this chapter, th e student shoul d the diet: the significance of essential amino acids, the concep t of nitroge n balance , th e meanin g o f obligator y nitroge n loss , and the natur e of protei n deficiency diseases .
