ABSTRACT
Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers-offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various special
TABLE OF CONTENTS
part 1|1 pages
Process Chemistry in the Pharmaceutical Industry: An Overview
chapter 1|18 pages
Ontazolast: The Evolution of a Process
Vittorio Farina, Karl Grozinger, Hermann Müller-Bötticher and Gregory P. Roth
chapter |13 pages
The Process Research and Development of DuPont Merck's Cyclic Urea Diols, A New Class of HIV Protease Inhibitors
Chemical Process Research & Development, The DuPont Merck Pharmaceutical Company, Chambers Works, Deepwater, NJ 08023
part 13|1 pages
Practical Enantio- and Diastereo-selective Processes for Azetidinones
chapter 14|20 pages
Synthesis of the Common Lactone Moiety of HMG-CoA Reductase Inhibitors
Dagenham Research Centre, Rhone-Poulenc Rorer Central Research, Rainham Road South, Dagenham, Essex, Essex RM10 7XS, UK
chapter 17|26 pages
Enantioselective Synthesis: The Optimum Process
John J. Partridge and Brian L. Bray
part |1 pages
Chiral (Salen)Mn(III) Complexes in Asymmetric Epoxidations: Practical Synthesis of c/s-AminoindanoI and Its Applications to Enantiopure D Synthesis
