Ataxia telangiectasia (AT) is an incurable, rare autosomal recessive genetic disorder which affects approximately one in 40,000-100,000 and the carrier frequency is estimated to be 1:100-200. In the United Kingdom it affects 1 in 300,000 live births amounting to about 5 or 6 cases per year. Although the medial survival rate of affected persons is b

chapter 1|6 pages

Clinical Features of AtaxiaTelangiectasia

chapter 3|9 pages

Cell Signaling in Ataxia Telangiectasia

chapter 11|8 pages

Animal Models for Ataxia Telangiectasia