Linear chromosomes represent an evolutionary innovation associated with the origin of eukaryotic cells. This book describes how linear chromosomes and primordial pathways for maintaining their terminal structures, telomeres, emerged in early eukaryotes.Telomeres, derived from the Greek meaning terminal part, were first described by Hermann Muller i

chapter 4|12 pages

T-Loops,T-Circles and Slippery Forks

chapter 5|13 pages

Molecular Diversity of Telomeric Sequences

chapter 6|17 pages

Evolution of Telomere Binding Proteins