ABSTRACT

While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. This text presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The author emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls.

part 1|2 pages

Part I The Basics

chapter 1|6 pages

Why Use Regression Models?

chapter 2|12 pages

An Introductory Example

chapter 3|2 pages

The Classical Multiple Regression Model

chapter 4|6 pages

Adjusted Effects

chapter 6|16 pages

Logistic Regression

chapter 8|16 pages

Categorical Covariates

chapter 10|12 pages

The Cox Proportional Hazards Model

chapter 11|10 pages

Common Pitfalls in Using Regression Models

part 2|2 pages

Part II Advanced Topics and Techniques

chapter 12|14 pages

Some Useful Technicalities

chapter 13|16 pages

Comparing Regression Coefficients

chapter 14|42 pages

Power and Sample Size

chapter 15|6 pages

Selection of the Sample

chapter 16|34 pages

Selection of Covariates

chapter 17|38 pages

Modelling Nonlinear Effects

chapter 18|10 pages

Transformation of Covariates

chapter 19|30 pages

Effect Modification and Interactions

chapter 20|14 pages

Applying Regression Models to Clustered Data

chapter 22|10 pages

The Impact of Measurement Error

chapter 23|6 pages

The Impact of Incomplete Covariate Data

part 3|2 pages

Part III Risk Scores and Predictors

chapter 24|22 pages

Risk Scores

chapter 25|12 pages

Construction of Predictors

chapter 26|10 pages

Evaluating the Predictive Performance

part 4|2 pages

Part IV Miscellaneous

chapter 28|10 pages

Alternatives to Regression Modelling

chapter 29|8 pages

Specific Regression Models

chapter 30|14 pages

Specific Usages of Regression Models

chapter 31|10 pages

What Is a Good Model?