ABSTRACT
Presents the Terminology and Methods of Mendelian Randomization for Epidemiological StudiesMendelian randomization uses genetic instrumental variables to make inferences about causal effects based on observational data. It, therefore, can be a reliable way of assessing the causal nature of risk factors, such as biomarkers, for a wide range of disea
TABLE OF CONTENTS
part |2 pages
I Using genetic variants as instrumental variables to assess causal relationships
part |2 pages
II Statistical issues in instrumental variable analysis and Mendelian randomization
part |2 pages
III Prospects for Mendelian randomization