ABSTRACT

In recent years researchers have gained a greater understanding of the immunological and inflammatory mechanisms underlying rheumatoid arthritis. Much of their efforts have centred on the role of the cytokine network in the pathophysiology of the disease. On the basis of these discoveries pharmaceutical companies have developed several potential bi

chapter 1|6 pages

The burden of rheumatoid arthritis

chapter 4|12 pages

The concept of IL-1Ra

The discovery of IL-1 receptor antagonist

chapter 5|6 pages

Current clinical management of RA

chapter 7|4 pages

Conclusion and future prospects