ABSTRACT

The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa

chapter 1|5 pages

0GENERAL INTRODUCTION

chapter 1|5 pages

1 Toxicity Assays

chapter 1|10 pages

2 Antimicrobial Assays

chapter 1|12 pages

3 Antiviral and Anticancer Assays

chapter 1|2 pages

4 Antimitotic Assay

chapter 1|7 pages

5 Genotoxicity Assays

chapter 1|15 pages

6 Assays for control of tropical diseases

chapter 1|9 pages

7 Assays for agrochemicals

chapter 1|7 pages

8 Hepatotoxicity assays

chapter 1|1 pages

10 Diuretic activity assay

chapter 1|3 pages

11 Anthelmintic activity assays

chapter 1|2 pages

12 Antifertility/Anti-implantation assays

chapter 1|1 pages

14 Anti-inflammatory Assay

chapter 1|2 pages

15 Immunomodulating Assay

chapter 1|3 pages

16 Antiepileptic (Anticonvulsant) assay

chapter 1|1 pages

17 Analgesic assays

chapter 1|3 pages

18 Gastroprotective/Antiulcer assays

chapter 1|2 pages

19 Radiolabelling bioassays

chapter 1|1 pages

20 Anti-emetic assay

chapter |2 pages

Part-B High-Throughput Screening

chapter 2|5 pages

1 Introduction

chapter 2|34 pages

2 Enzyme assays

chapter 2|25 pages

3 Cell-based receptor functional assays

chapter 2|22 pages

4 Radioligand binding assays