ABSTRACT

Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.

chapter 1|9 pages

Scope of Toxicology

chapter 2|6 pages

Stages in the Induction of Toxicity

chapter 3|12 pages

Kinetics and End-points

chapter 4|7 pages

Acute and Chronic Intoxication

chapter 6|5 pages

2 Bioactivation

chapter 6|2 pages

4 Cytochrome P450s

chapter 6|4 pages

5 Active Transport of Intoxicants

chapter 6|1 pages

8 Discussion

chapter 6|2 pages

9 Summary

chapter 7|37 pages

Initiating Reactions with Targets

chapter 11|13 pages

Biomonitoring

chapter 12|15 pages

Epidemiology

chapter 13|12 pages

Environmental and Ecotoxicology

chapter 14|8 pages

Reflections, Research and Risk