By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and

chapter 1|9 pages

General Introduction

chapter 2|9 pages

Study Design and Regulatory Requirements

chapter 3|21 pages

Preanalytical and Analytical Variables

chapter 4|14 pages

Statistical Approaches

chapter 5|12 pages

General Enzymology

chapter 6|17 pages

Assessment of Hepatotoxicity

chapter 7|12 pages

Assessment of Nephrotoxicity

chapter 8|37 pages

Assessment of Endocrine Toxicity

chapter 11|8 pages

Assessment of Neurotoxicity

chapter 12|15 pages

Electrolyte and Fluid Balance

chapter 13|9 pages


chapter 14|12 pages