ABSTRACT

Principles of Proteomics is designed specifically to explain the different stages of proteomic analysis, their complexities and their jargon to students and researchers in a non-technical overview of the field.

The author describes the broad range of problems which proteomics can address, including structural proteomics, interaction proteomics, protein modification analysis and functional proteomics.  Methodologies are described in user-friendly language, from the more traditional two-dimensional gel electrophoresis to the new developments in protein chip technologies.  These are well presented in the context of overall strategies which can be adopted to address the different aspects of large-scale protein analysis.

chapter 1|23 pages

From genomics to proteomics

chapter 2|27 pages

Strategies for protein separation

chapter 3|21 pages

Strategies for protein identification

chapter 4|19 pages

Strategies for protein quantitation

chapter 6|32 pages

Structural proteomics

chapter 7|38 pages

Interaction proteomics

chapter 8|30 pages

Protein modification in proteomics

chapter 9|27 pages

Protein chips and functional proteomics

chapter 10|20 pages

Applications of proteomics