ABSTRACT
This book describes a unique combination of research programs based on a striking variety of hypotheses and procedures directed toward understanding the sources and consequences of neurobehavioral plasticity. This remarkable attribute of the nervous system -- to be pliable and capable of being shaped or formed by natural or artificial sources toward adaptation or maladaptation -- is considered in terms of the neurochemical forces and neuroanatomical structure that has been found to be pivotal for this function. The impetus for this volume was a symposium held to honor Robert L. Isaacson for his scientific and pedagogical achievements as well as his contributions to behavioral neuroscience.
Corresponding to his three major research interests, the book is divided into three sections as follows:
* the first explores the relationship between the limbic system and behavior, with an emphasis on learning and memory;
* the second considers -- through a wide range of approaches -- issues of plasticity in behavior and brain; and
* the third deals with neural and chemical determinants of normal and abnormal behavior.
This volume is not only a fitting tribute to Isaacson, but also an unusual collection of new evidence, procedures, and theories destined to have significant influence on behavioral neuroscience.
TABLE OF CONTENTS
part 1|133 pages
Limbic System and Behavior
chapter 2|18 pages
The Hippocampus and Complex, Nonspatial Discrimination
chapter 6|18 pages
Septal Regulation of the Hippocampal-Entorhinal Network
part 2|134 pages
Plasticity in Behavior and Brain
chapter 10|19 pages
Structure and Plasticity of the Hebbian Synapse
chapter 13|12 pages
Hebbian Plasticity in the Hippocampus
part 3|29 pages
Neural and Chemical Determinants of Normal and Abnormal Behavior