ABSTRACT

Continuing a long tradition, Lu‘s Basic Toxicology, Seventh Edition, provides guidance on principles of toxicology and testing procedures for toxicities as well as a concise yet detailed mechanism of both target organ and non-target organ toxicities. The book also addresses the toxic effects of chemicals and risk assessment, giving students and practicing toxicologists, the tools to enhance their practice. This edition includes new chapters on Systems Toxicology, Chemicals and Children, Toxicology of Reproductive Systems, providing the essentials of these topics in the same style as other chapters in the book. Separate subject and chemical indexes make this a useful, quick shelf reference.

section Section one|158 pages

General principles of toxicology

chapter Chapter one|19 pages

History of toxicology

chapter Chapter two|21 pages

Toxicokinetics of xenobiotics

chapter Chapter three|19 pages

Biotransformation of toxicants

chapter Chapter four|25 pages

Mechanisms of toxic effects

chapter Chapter five|19 pages

Modifying factors of toxic effects

chapter Chapter six|20 pages

Conventional toxicity studies

chapter Chapter seven|28 pages

Systems toxicology

section Section two|92 pages

Testing procedures for nontarget organ toxicities

chapter Chapter eight|32 pages

Carcinogenesis

chapter Chapter nine|21 pages

Mutagenesis

chapter Chapter ten|17 pages

Developmental toxicology

chapter Chapter eleven|18 pages

Toxicology of lactation

section Section three|181 pages

Target organs and systems

chapter Chapter twelve|18 pages

Toxicology of the liver

chapter Chapter thirteen|23 pages

Toxicology of the kidney

chapter Chapter fourteen|14 pages

Toxicology of the immune system

chapter Chapter fifteen|15 pages

Respiratory system toxicology

chapter Chapter sixteen|14 pages

Toxicology of the skin

chapter Chapter seventeen|13 pages

Toxicology of the eye

chapter Chapter eighteen|20 pages

Toxicology of the nervous system

chapter Chapter nineteen|14 pages

Toxicology of the cardiovascular systems

chapter Chapter twenty|18 pages

Toxicology of the reproductive systems

chapter Chapter twenty-one|27 pages

Toxicology of endocrine-disrupting chemicals

section Section four|190 pages

Toxic substances and risk assessment

chapter Chapter twenty-two|17 pages

Food additives, contaminants, and safety

chapter Chapter twenty three|33 pages

Toxicity of pesticides

chapter Chapter twenty-four|16 pages

Nanotoxicology

chapter Chapter twenty-five|25 pages

Toxicity of metals

chapter Chapter twenty-six|14 pages

Environmental pollutants

chapter Chapter twenty-seven|16 pages

Occupational toxicology

chapter Chapter twenty-eight|19 pages

Exogenous agents and childhood exposure

chapter Chapter twenty-nine|17 pages

Clinical toxicology

chapter Chapter thirty|26 pages

Risk assessment and regulatory toxicology