The triple helix of university–industry–government interactions is a universal model for the development of the knowledge-based society, through innovation and entrepreneurship. It draws from the innovative practice of Massachusetts Institute of Technology (MIT) with industry and government in inventing a regional renewal strategy in early 20th-century New England. Parallel experiences were identified in “Silicon Valley,” where Stanford University works together with industry and government. Triple helix is identified as the secret of such innovative regions. It may also be found in statist or laissez-faire societies, globally.

The triple helix focuses on “innovation in innovation” and the dynamic to foster an innovation ecosystem, through various hybrid organizations, such as technology transfer offices, venture capital firms, incubators, accelerators, and science parks.

This second edition develops the practical and policy implications of the triple helix model with case studies exemplifying the meta-theory, including:

• how to make an innovative region through the triple helix approach;

• balancing development and sustainability by “triple helix twins";

• triple helix matrix to analyze regional innovation globally; and

• case studies on the Stanford's StartX accelerator; the Ashland, Oregon Theater Arts Clusters; and Linyi regional innovation in China.

The Triple Helix as a universal innovation model can assist students, researchers, managers, entrepreneurs, and policymakers to understand the roles of university, industry, and government in forming and developing “an innovative region,” which has self-renewal and sustainable innovative capacity.

chapter |17 pages


Triple helix: a universal innovation model?

part 1|102 pages

The triple helix concept

chapter 1|19 pages

A Universal Triple Helix

Silicon Valley’s secret

chapter 2|17 pages

Triple Helix in Civil Society

chapter 4|20 pages

The Firm in a Triple Helix

chapter 5|21 pages

The Optimum Role of Government

part 2|116 pages

The triple helix innovation model

chapter 6|22 pages

Triple Helix Region

chapter 7|18 pages

The incubation of innovation

chapter 8|19 pages

Triple Helix Technopolis

chapter 9|22 pages

Venture Capital in the Triple Helix

chapter 10|18 pages

Triple Helix Twins

Balancing development and sustainability

chapter 11|17 pages

Triple Helix Matrix

part 3|62 pages

Case studies

chapter 12|19 pages

The Triple Helix in Silicon Valley

chapter 13|19 pages


Filling the gap in Stanford University’s entrepreneurial development

chapter 14|23 pages

A Teaching University’s Civic Entrepreneurship

Ashland Oregon theater cluster and renaissance as a humanities town 1

part 4|18 pages


chapter 15|18 pages

Innovation in innovation

An endless transition toward the triple helix