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A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

Book

A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

DOI link for A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery book

A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

DOI link for A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery

A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery book

ByTaosheng Chen
Edition 1st Edition
First Published 2009
eBook Published 21 December 2009
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/9781420070514
Pages 291
eBook ISBN 9780429138263
Subjects Bioscience
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Chen, T. (2009). A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery (1st ed.). CRC Press. https://doi.org/10.1201/9781420070514

ABSTRACT

The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor. However, few scientists have the multidisciplinary experience needed to control all aspects of an HTS drug discovery project. A P

TABLE OF CONTENTS

chapter 1|24 pages

Assay Development for Protein Kinases and Phosphatases

chapter 2|24 pages

Fluorescence-Based Biochemical Protease Assay Formats

chapter 3|10 pages

Assay Development for Nuclear Hormone Receptors

chapter 4|24 pages

Assay Development for G Protein-Coupled Receptors and Ion Channels

chapter 5|16 pages

Assay Development for Heat Shock Proteins

chapter 6|24 pages

Assay Development for Cell Viability and Apoptosis for High-Throughput Screening

chapter 7|20 pages

Assay Development for Antimicrobial Drug Discovery

chapter 8|14 pages

Image-Based High Content Screening

chapter 9|12 pages

Application of RNA Interference in Drug Discovery

chapter 10|14 pages

Assay Development Using Primary and Primary-Like Cells

chapter 11|10 pages

Screening Automation

chapter 12|20 pages

Compound Library Management

chapter 13|20 pages

Unique Discovery Aspects of Utilizing Botanical Sources

chapter 14|32 pages

Screening Informatics

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