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Book

G Protein-Coupled Receptors

Book

G Protein-Coupled Receptors

DOI link for G Protein-Coupled Receptors

G Protein-Coupled Receptors book

Structure, Function, and Ligand Screening

G Protein-Coupled Receptors

DOI link for G Protein-Coupled Receptors

G Protein-Coupled Receptors book

Structure, Function, and Ligand Screening
Edited ByTatsuya Haga, Shigeki Takeda
Edition 1st Edition
First Published 2005
eBook Published 4 August 2005
Pub. Location Boca Raton
Imprint CRC Press
DOI https://doi.org/10.1201/9781420038279
Pages 336
eBook ISBN 9780429129889
Subjects Bioscience
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Haga, T., & Takeda, S. (Eds.). (2005). G Protein-Coupled Receptors: Structure, Function, and Ligand Screening (1st ed.). CRC Press. https://doi.org/10.1201/9781420038279

ABSTRACT

This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation.

TABLE OF CONTENTS

part |2 pages

Part I Screening of Ligands for GPCRs

chapter 1|34 pages

Screening of Endogenous Ligands for Orphan GPCRs

ByMasaaki Mori, Shuji Hinuma, Tetsuya Ohtaki, Masahiko Fujino

chapter 2|30 pages

Screening of Ligands for Human GPCRs by the Use of Receptor-Gα Fusion Proteins

ByShigeki Takeda, Hinako Suga, Tatsuya Haga

chapter 3|18 pages

Screening and Identification of Ghrelin, an Endogenous Ligand for GHS-R

ByMasayasu Kojima, Kenji Kangawa

chapter 4|26 pages

Ligand Screening of Olfactory Receptors

ByKazushige Touhara, Sayako Katada, Takao Nakagawa, Yuki Oka

part |2 pages

Part II Functions and Regulations of GPCRs

chapter 5|24 pages

Generation and Phenotypical Analysis of Muscarinic Acetylcholine Receptor Knockout Mice

ByJürgen Wess, Dinesh Gautam, Sung-Jun Han, Jongrye Jeon, Cuiling Li

chapter 6|42 pages

Systematic Mutagenesis of M Muscarinic Acetylcholine Receptors

ByEdward C. Hulme

chapter 7|18 pages

Analysis of the Regulation of Muscarinic Acetylcholine Receptors

ByChris J. van Koppen

chapter 8|22 pages

Single-Molecule Analysis of Chemotactic Signaling Mediated by cAMP Receptor on Living Cells

ByMasahiro Ueda, Yukihiro Miyanaga, Toshio Yanagida

chapter 9|26 pages

Oligomerization of G Protein-Coupled Purinergic Receptors

ByHiroyasu Nakata, Kazuaki Yoshioka, Toshio Kamiya

part |2 pages

Part III Tertiary Structure of GPCRs and Their Ligands

chapter 10|18 pages

Methods and Results in X-Ray Crystallography of Bovine Rhodopsin

ByTetsuji Okada, Rumi Tsujimoto, Miho Muraoka, Chihiro Funamoto

chapter 11|22 pages

Determination of Steric Structure of Muscarinic Ligands Bound to Muscarinic Acetylcholine Receptors: Approaches by TRNOE (Transferred Nuclear Overhauser Effect)

Edited ByTatsuya Haga, Shigeki Takeda

chapter 12|20 pages

Modeling of G Protein-Coupled Receptors for Drug Design

ByMasaji Ishiguro
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