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ByDominant Negative RARs in F9 Cells Espeseth et aL an F9-derived cell line expressing a fusion between and the A-D region of RARao Expression of this chimeric-truncated receptor leads to inhibition of RA-dependent differentiation of the cells and, to inhibition of expression of only a subset of RP, the case, chimeric-truncated receptors could also interfere with other transacti- vation circuits dependent on these TIF'so Care should therefore be exercised in taking the Espeseth et al. results as direct evidence for RAR functions in differen- tiation of F9 cell!L 3. RA-Resistant
Edition 1st Edition
First Published 1994
Imprint CRC Press
Pages 4
eBook ISBN 9780429081293
