ABSTRACT

This is a more or less complete loss of the lateral part of the eyebrows, which is one of the most important

atopy stigmata

(see

Hanifin and Rajka criteria

).

5-HETE

5S-hydroxyeicosatetraenoic acid is derived from

-

HPETE

. This intermediate in

eicosanoid

metabolism (see

leukotrienes

) can act as an inflammatory

mediator

. It shares some biological activities with LTB

, although it is less potent.