ABSTRACT

The arterial gas tension of carbon dioxide. Normal range 4.5 to 6.3 kilopascals (kPa). Low values indicate

hyperventilation

, whereas high values indicate alveolar hypoventilation.

PAF

(See

platelet

-

activating factor

.)

PAF-ACETYLHYDROLASE

Platelet

-

activating factor

(PAF) acetylhydrolase catalyzes the degradation of PAF and related phospholipids, which have proinflammatory, allergic, and prothrombotic properties. Deficiency of plasma PAF acetylhydrolase is an autosomal (see

autosome

)

recessive

disorder that has been associated with severe

asthma

in Japanese children. Acquired deficiency has been described in several human diseases usually associated with severe

inflammation

.