ABSTRACT
A and B. Tachykinins are almost exclusively localized to neurones, both in the central and peripheral
nervous system
. Substance P and neurokinin A are found in the airways, and the levels of these tachykinins are affected by age, cigarette
smoking
, and various pathological processes. Tachykinin
receptors
are present on
smooth muscle
,
submucosal glands
, and vascular
endothelial cells
in the airways, and mediate nonadrenergic noncholinergic (see
nonadrenergic noncholinergic nerves
)
airway obstruction
.
TACROLIMUS
