ABSTRACT

B) in HIV-infected cells, virus transcription, and replication. Certain medications, however, may interact with NAC and should be avoided.

The isomers of NAC, LNAC, and DNAC were recently found by Neal and coworkers (2003) to be effective antioxidants, protecting mice lung from increased malondialdehyde levels

and mice liver from increased 8-hydroxy-deoxyguanosine, following 18 Gy whole-body radiation. These results were consistent with the radioprotection and repair processes associated with NAC. Serrano-Mollar et al. (2003) found NAC reduced primary inflammatory events, which prevented cellular damage and pulmonary-fibrosis development in bleomycininduced lung damage in rats.