ABSTRACT
B) (Sandoval-Chacon et al., 2002; Akesson et al., 2003). A hot-water extract from the bark of
Uncaria tomentosa,
C-Med 100
,
in which large molecules, such as tannins and flavonoids, had been removed
,
still enhanced DNA repair (Sheng et al., 2000) and protected against “spontaneous” apoptosis induction
in vitro
(Akesson et al., 2003). It also inhibited proliferation of tumor cells without inducing apoptosis or necrotic cell death. Subsequent work by Akesson et al. (2005) identified quinic acid as one of the components responsible for these effects.
