ABSTRACT
Unlike pharmaceutical agents whose interactions with biology are largely chemical in nature, medical nanorobots will interact both chemically and mechanically (Chapter 15.1) with human tissues and cells. Similarly, traditional biomedical device implants (Section 15.2.1) produce both chemical and bulk mechanical6049 effects, but nanoorgans and nanoaggregates include active nanoscale features and moving parts that can apply spatially heterogeneous mechani cal forces at the microscopic and molecular scale. Thus any discus sion of biocompatibility in nanomedicine must necessarily include an analysis o f the m echanical biocom patib ility ,5728 or mechanocompatibility, o f nanorobotic systems as they interact with the tissues and cells of the human body.
