ABSTRACT

Placenta has previously been show n to have high levels o f ADM m R N A .1 However, no ADM b ind ing sites o r im m unoreactivity w ere detec ted in p lacen ta . It is w ell know n tha t ADM is released from o ther tis­ sues and cells, for exam ple endothelial cells, which contain high levels o f ADM mRNA, b u t lit tle im m u n o re ac tiv ity .4 T herefo re isolated rat placentae were investigated for release o f ADM im m unoreactivity.