ABSTRACT

INTRODUCTION In vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cycles have shown that women have only a nite number of gametes out of a pool of collected oocytes that are viable for generating a term pregnancy. is demonstrates the need for simple methods of preimplantation embryo assessment in the prediction of pregnancy rates. In this respect, intensive research has been done at the zygote stage on day 1 of preimplantation development.