ABSTRACT

During the last two decades a strong scientific interaction developed between the laboratory of Bob Isaacson and the Department of Medical Pharmacology of the Rudolf Magnus Institute. Although for years the neural mechanisms of grooming behavior of rats were a focal point in that collaboration, the neurobiology of learning and memory processes with special reference to the role of the hippocampus was and is a subject that is actively researched by both teams of investigators. In this chapter, we review some aspects of hippocampal synaptic plasticity presumed to be of significance to learning and memory processes.