Unbalanced, sensitive, and easily wounded, people often fall into just such a pitiful state. A careless critical review or a look of indifference may be enough to send them into depression. It is also true that a fairly small success might lift their spirits and make them forget their hopeless thoughts. Once again, they are full of faith and power. Their entire lives consist of such endless fluctuations. Such periods of artistic decline are not trifles. They are complicated and tangled phenomena. They know too little about them to draw any kind of final conclusions. By all appearances, these ascents and descents are subordinate to certain laws. Some of these known laws are prompted to us by the physiology. They connect periods of creative decline with physical exhaustions, the change of seasons as well as solar activity. Most importantly, these fluctuations are connected with the critical cycles in the life of the body, such as changes in the endocrine system.