ABSTRACT

Carotenoids play a pivotal role in the treatment of a wide range of diseases, with their potential antioxidant and anti-inflammatory properties. This chapter highlights the importance of retinoic acid, all-trans retinoic acid, lycopene, β-carotene, xanthophyll carotenoids, such as astaxanthin and fucoxanthin, in the treatment of Alzheimer’s disease (AD). The value of combination treatments, such as xanthophylls and omega-3 fatty acids, is discussed. This chapter also focuses on challenges associated with these important carotenoids and the use of different drug delivery systems in attempts to overcome these problems. The significance of nanotechnology in overcoming phytochemical bioavailability issues is emphasized.