ABSTRACT
This chapter presents a case study of a 55-year-old man who is presented with a 3-day history of a productive cough and shortness of breath. He has a history of chronic obstructive pulmonary disease (COPD) with frequent exacerbations but no previous intensive care admissions. The patient presents with symptoms and signs suggestive of sepsis, likely arising from a chest infection. The initial resuscitation provided to the patient is appropriate. The goal of initial resuscitation is to restore perfusion and prevent or limit organ dysfunction. The term 'early goal-directed therapy' (EGDT) refers to the administration of intravenous fluid within the first 6 hours of presentation that uses various physiologic targets to direct fluid management. In addition to achieving haemodynamic stability, it is important to be aware of additional aspects of managing septic shock, which include appropriate management of diabetes and insulin.
