ABSTRACT
Abstract .............................................................................................................351 17.1 Introduction............................................................................................352 17.2 Occurrence of Catechins........................................................................354 17.3 Chemical Structures of Catechins and Their Biological Activities ......354 17.4 Inhibition of Carcinogenesis by Catechins in Animal Models.............355 17.5 Chemoprevention of Human Cancer by Tea Drinking .........................355 17.6 Biochemical and Molecular Mechanisms of Cancer
Chemoprevention by Catechins.............................................................356 17.6.1 Antioxidant Effects of Catechins ..............................................356 17.6.2 Pro-Oxidant Effects of Catechins..............................................357 17.6.3 Induction of Apoptosis and Cell Cycle Arrest..........................358 17.6.4 Inhibition of Cellular Proliferation and Tumor Progression
through Suppressing EGFR Signaling ......................................358 17.6.5 Inhibition of iNOS through Downregulating NF
κB Activation...................................................................................359
