ABSTRACT
A common assumption in biomaterials research is that cellular interactions with natural and artificial surfaces are mediated through adsorbed proteins. Such diverse processes as
thrombosis
and
hemostasis
, hard and soft tissue healing, infection, and inflammation are each affected by protein adsorption to surfaces
in vivo
. Many
in vitro
diagnostic analyses, chromatographic separation techniques, and genetic engineering processes also involve protein adsorption at solid-liquid interfaces.
