An updated version of chronic catathymic homicides reviews research along with new cases with analysis. The chronic form of catathymic process is differentiated from the acute, with special sections emphasizing Reid Meloy’s contributions, the predominant role of depression, obsessions, stalking and catathymic homicide, catathymic mass murder, and recent research on catathymic familicide and youthful familicidal offenders. The chapter concludes with a discussion of issues involving prevention.