ABSTRACT
Surfaces ................................................................................................................... 113 3.3.13 Thermally Mediated Nanopropulsion ................................................................ 118 3.3.14 Polymeric Nanopropulsion Engine ..................................................................... 119 3.3.15 Stepped Nanomagnetic Rotary Propulsion ....................................................... 119 3.3.16 Undulating Wave Locomotion ............................................................................. 121 3.3.17 Deformative Electroactive Polymers ................................................................... 122
3.4 Potential Nanomedical Surface Ambling Strategies ..................................................... 124 3.4.1 Acto-Myosin Complex........................................................................................... 125 3.4.2 Actin Filaments ...................................................................................................... 127 3.4.3 Kinesin ..................................................................................................................... 128 3.4.4 Dynein ..................................................................................................................... 129 3.4.5 Microtubules ........................................................................................................... 130
Two of the most daunting interlinked sets of challenges that visionists, designers, and engineers will confront in the conceptualization of advanced nanomedical devices and systems are the development of practicable and efcient nanoscale propulsive mechanisms and their associated navigational infrastructures to provide for their precise control. Robust and high-performance nanopropulsion components will have the prerequisite of being broadly adaptable under myriad in vivo physiological conditions. Navigational strategies will likely encompass and be imbued with the capacity for mediating the pace and precise orientation, in real time, of perhaps thousands or millions of autonomous nanomedical devices that perform medically benecial functions simultaneously to address a wide range of disease states.
