ABSTRACT

Polymeric materials play a critical role in the development of solid oral dosage forms and this contribution is likely to grow continuously in the foreseeable future as products continue to become more technologically advanced. Polymers provide a basis for the development of controlled release systems and the stabilization of amorphous forms, presenting two unique delivery platforms which have contributed to the advancement of patient care. As scientists continue to develop a deeper and more complete understanding of the underlying interactions, and the impact of such behaviors on dosage form performance, pharmaceutical systems will continue to become more complex and more efficacious. Polymeric systems are also likely to provide significant contributions in many growing areas of pharmaceutical development, particularly for advanced device manufacturing and bionanotechnology applications. Many of the newest hybrid technologies exploit specific polymeric interactions in order to provide enhanced pharmaceutical efficacy.