ABSTRACT
In recent years, the self-assembly of novel copolymer-based nanostructures in solution have been extensively applied in biomedical field. The interest in such nanomaterials lies in the fact that their dimensions, in the nanoscale range (near to 100 nm), and physicochemical factors make it possible to fabricate materials with exclusive properties and technological aspects. In this entry, we describe the most significant biomedical applications of polymeric nanospheres, nanotubes, and nanoparticles, in particular, what can be achieved through molecular self-assembly of copolymers. First, the basic principles of self-assembly of block copolymers in solution will be discussed. An overview of the physicochemical properties of amphiphilic copolymers will be then given, including selected drug-polymer aspects. Finally, we will concentrate on applications such as delivery, therapeutics, and theranostics in biomedical field.
