ABSTRACT
Therapeutic drugs are often given systemically. Once given systemically, a drug will distribute throughout the body. By distributing in the body, the drug is essentially diluted out from its original concentration in the formulation/dosage form. In order to obtain a solution formulation for drugs with poor solubility, it is necessary to alter the formulation to facilitate solubilization. This entry is designed to summarize the theoretical as well as practical use of each solubilization technique.
