ABSTRACT
Population pharmacokinetics (PPK) is an area of clinical pharmacology, which aims at the quantitative assessment of between and within individual variability in drug absorption, distribution, metabolism, and excretion. This entry presents the theoretical background of PPK, the different approaches to estimate PPK and their respective advantages and disadvantages, how PPK is applied to different data types, and how PPK studies can be prospectively designed to maximize knowledge discovery and creation in drug development.
