ABSTRACT

Health benefits of soya isoflavones (IFs) for prevention of certain cancers, osteoporosis, and climacteric symptoms at menopause have been recognized by many epidemiological studies. A recent recommendation to use soy protein or IFcontaining tablets, however, does not stand on firm evidence that clarifies safety and toxicity potential in humans. Various mechanisms of IF action have been found, in addition to classical action as phytoestrogens. Absorption, distribution, and excretion of IF have been clarified, but internal metabolism and interaction with macromolecules in the body need further study. Recent research on IF, including analytical methods, is reviewed in this chapter.