ABSTRACT

Concentrations measured at fixed locations can be dramatically different from those incorporated by personal exposure assessments made in the same space (Rodes et al., 1991). The concept that measurements of concentration do not necessarily quantify actual human exposures is illustrated by the classical risk paradigm (Rodes and Wiener, 2001):

sources→emissions→concentrations→exposures→doses→effects

where sources produce emissions that result in microenvironmental concentrations that result in exposures that are dependent on influencing factors, especially time-weighted proximity to the emissions from localized sources. The actual exposures produce body doses, dependent on uptake factors such as the inhalation rate, that can ultimately result in adverse health effects in susceptible populations.