Different people display individual patterns of susceptibility to biogenic amines in foods. Clinical signs of histamine poisoning are more severe in people taking medications which inhibit enzymes that normally detoxify histamine in the intestines. Symptoms may be gastrointestinal (nausea, vomiting, diarrhea), circulatory (hypotension), or cutaneous (rash, urticaria, palpitations, tingling,

flushing, burning, or itching). Antihistamines may be used effectively to treat the symptoms.