ABSTRACT
VITAMIN C AND INFECTIOUS DISEASE: A REVIEW OF THE LITERATURE AND THE RESULTS OF A RANDOMIZED, DOUBLE-BLIND,
PROSPECTIVE STUDY OVER 8 YEARS
Maxine Briggs
TABLE OF CONTENTS
I. Review of the Literature.............................................................................................. 40 A. In Vitro Studies................................................................................................. 40 B. Animal Studies....................................................................................................40 C. High-Dose Vitamin C and the Common Cold................................................ 40 D. Vitamin C in Other Infections........................................................................... 46 E. Wound Healing...................................................................................................57 F. Conclusions........................................................................................................ 57
II. Clinical Investigation: An 8-Year, Prospective, Double-Blind Study of High-vs. Low-Dose AA Supplementation for the Prevention of Common C olds............... 57 A. Introduction........................................................................................................ 57 B. Methods and M aterials..................................................................................... 59 C. Results and Discussion..................................................................................... 60 D. Conclusions........................................................................................................65
