ABSTRACT

The routine use of cross-sectional imaging in the staging of intra-abdominal and extra-abdominal malignancy has shown that the adrenal gland is a frequent site of unexpected metastatic disease, with adrenal lesions being demonstrated in up to 6% of patients undergoing imaging studies. Although modern computed tomography (CT) and magnetic resonance imaging (MRI) can be expected to detect nodules exceeding 5–10 mm, autopsy studies show that many adrenal metastases frequently go undetected because of their small size.