ABSTRACT

The inhibition of glucose digestion and absorption is dependent upon the continued actions of the dietary fiber to elevate the viscosity of the gastrointestinal contents, although factors other than the viscosity alone contribute to the resultant glycemia. Diabetes mellitus is a descriptive term covering a heterogeneous group of chronic metabolic disorders, all characterized by elevated blood glucose concentrations. Impairment of insulin action and eventual loss of insulin secretory capacity impacts on glucose metabolism primarily in the liver and skeletal muscles. Numerous reports have examined the actions of different test meals on the postprandial blood glucose and insulin profiles of diabetics. Oral propionate, supplied in capsules, had no impact on blood glucose levels, although oral glucose tolerance was marginally improved. The goals of dietary therapies in the management of type 2 diabetes must then take into account the impact the dietary prescription has on both blood glucose and lipid levels.