ABSTRACT

Biomaterials can be broadly defined as specially designed inorganic materials (e.g., ceramics, metals) and organic polymers (e.g., natural or synthetic polymers or their surface-modified versions) whose surfaces are in direct contact with biological components such as blood, tissue fluid, proteins, cells, etc. The interaction of these substrates with biological components, including covalent coupling, and adsorption of these materials on polymer surfaces depend greatly on their surface properties, including surface energy, surface functionality, composition, and surface morphology.