ABSTRACT
The biohybrid artificial pancreas (BAP) represents one of the most challenging, complex, and promising applications of a relatively new science: tissue engineering. Tissue engineering has been defined as ‘‘an interdisciplinary field which applies the principles of engineering and life sciences towards the development of biological substitutes that aim to maintain, restore or improve tissue function’’ (1). Sometimes, even excellent artificial devices must comply with restrictions and specific requirements associated with the biological counterpart, in order to secure optimal functional performance.
