ABSTRACT
The utility of this dual microsensor has been tested at bovine adrenal medullary cells [45]; however, the technique has the potential to be used at other cultured cell types, including PC12 cells. The sensor has a subsecond response time for both Ca2+ and catecholamine concentration changes, and Ca2+ concentrations as low as 100 nM can be detected while the detection limit for catecholamine is in the micromolar range.
