ABSTRACT

Figure 15 Current-time traces for exocytosis at single PC12 cells. A 6 s ejection of stimulant [105 mM K+ (A), 1 mM nicotine (B), or 1 mM muscarine (C)] from a microinjector was administered at each arrow. The resulting current transients correspond to the oxidation of DA at the electrode tip as it is released from the cell. Detection was performed using a 5 µm carbon fiber electrode in the amperometric mode at 0.65 V versus SSCE. (Reproduced from J. Neurochem. with permission [18].)